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For example, the administration of a κ‐opioid receptor antagonist before stress induction improved stress impacts on disrupted sleep and circadian rhythms and diminished alterations in mPer2 gene expression in the nucleus accumbens (NAc), 82 a brain region involved in the sleep/wake regulation

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The success of biologics targeting TNF-α, IL-17, and IL-23 has transformed therapies for psoriasis treatment

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