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NOT-SO-SIMPLY STATED The use of modifier –25 in conjunction with intravitreal injection is often, but not always, appropriate and correct coding that recognizes the performance of a significant, separately identifiable service when there is medical necessity

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9 Though the reason for these differences has not been fully elucidated, one study hypothesized that the impacts on hemoglobin and hematocrit are more significant with high transient testosterone spikes associated with injectable testosterone, leading to an exacerbated impact of injectable testosterone esters on these parameters