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Importantly, commonly used in vitro BBB models, such as transwell systems and endothelial cell lines including RBE4, bEnd.3, and hCMEC/D3 monolayers, have important limitations, as they may overpredict permeability and do not fully recapitulate key in vivo BBB features, including physiological shear stress and multicellular neurovascular architecture (Chaulagain et al., 2023)

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Potency:2.5 mg Orange

a frameshift is the end of useful information - treat the start of a frameshift as a stop- gained PEAKs identifies a transcript by and passes-through the Accession ⁇ Entry Name portion of the FAST A header: ⁇ Accession PA-ensembl_transcript_name (to differentiate between different transcripts