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Furin also known as proprotein convertase 3 (PC3) is responsible for activation of SARS-CoV-2 which may be the reason for higher severity in terms of rapid transmission as compared to SARS- CoV
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ROS could oxidize the reactive cysteine residues in KEAP1 [71], inducing its conformational changes and inactivation, preventing NRF2 ubiquitination and degradation
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